in 4 days Aetna (CVS Health) — Zepbound back as additional preferred on templates See the changelog
WalletNoise

Zepbound® (tirzepatide) — 12.5 mg

Your cheapest verified route right now

verified price

$25 /month

Plan coverage + Zepbound Savings Card

Verified Sep 5, 2026 · zepbound.lilly.com

Per year at 12 fills
$300

Savings-card runway · 2026

year so far card covers through the Jan 1 reset

Savings-card math: at the maximum monthly benefit your card's annual cap runs out around Oct 27, 2027. Plan the next route before then, not after.

Ramp cost calculator

What the climb costs

Close

Both doses are yours to state, not ours to suggest. WalletNoise prices the schedule you describe and never recommends a dose, a target, or a pace — that is your prescriber's call.

12-month total $325 13 fills
Average per fill $25 peak $25
Flat at 12.5 mg $325 what multiplying today's price gives you
Cost per fill, 2.5 mg to 12.5 mg
  • 2.5 mg 5×
  • 5 mg 2×
  • 7.5 mg 1×
  • 10 mg 1×
  • 12.5 mg 4×
$0 $50 $100 2.5 mg — $25 $25 Sep2.5 mg — $25 Oct2.5 mg — $25 Nov2.5 mg — $25 Dec2.5 mg — $25 Jan5 mg — $25 Feb5 mg — $25 Mar7.5 mg — $25 Apr10 mg — $25 May12.5 mg — $25 Jun12.5 mg — $25 Jul12.5 mg — $25 Aug12.5 mg — $25

Fills at each dose on the way up

Reset to the label minimum
  • 2.5 mg −5 +
  • 5 mg −2 +
  • 7.5 mg 1 +
  • 10 mg 1 +
  • 12.5 mg then hold

Minus stops at the label's minimum interval — this never shows a schedule faster than the manufacturer's. Staying longer on a dose is yours to choose.

Every fill, dated and priced (13)
  1. 1 Sep 27, 2026 2.5 mg Plan coverage + Zepbound Savings Card $25
  2. 2 Oct 25, 2026 2.5 mg Plan coverage + Zepbound Savings Card $25
  3. 3 Nov 22, 2026 2.5 mg Plan coverage + Zepbound Savings Card $25
  4. 4 Dec 20, 2026 2.5 mg Plan coverage + Zepbound Savings Card $25
  5. 5 Jan 17, 2027 2.5 mg Plan coverage + Zepbound Savings Card $25
  6. 6 Feb 14, 2027 5 mg Plan coverage + Zepbound Savings Card $25
  7. 7 Mar 14, 2027 5 mg Plan coverage + Zepbound Savings Card $25
  8. 8 Apr 11, 2027 7.5 mg Plan coverage + Zepbound Savings Card $25
  9. 9 May 9, 2027 10 mg Plan coverage + Zepbound Savings Card $25
  10. 10 Jun 6, 2027 12.5 mg Plan coverage + Zepbound Savings Card $25
  11. 11 Jul 4, 2027 12.5 mg Plan coverage + Zepbound Savings Card $25
  12. 12 Aug 1, 2027 12.5 mg Plan coverage + Zepbound Savings Card $25
  13. 13 Aug 29, 2027 12.5 mg Plan coverage + Zepbound Savings Card $25
This is arithmetic, not a plan. Fills are spaced 28 days apart — the label's own supply length — and priced on the date each one falls, so dated price changes are already included. Your prescriber decides whether you step at all, and many people stay at a lower dose.
The label's own words (once weekly)

Initiate at 2.5 mg once weekly for 4 weeks. After 4 weeks, increase to 5 mg once weekly. The dosage may be increased in 2.5 mg increments after at least 4 weeks on the current dosage. The 2.5 mg dosage is for initiation and is not approved as a maintenance dosage. Maximum 15 mg once weekly.

Verified Aug 31, 2026 ·pi.lilly.com

Every route we can price

Verified prices outrank cheaper estimates. Reference rows inform, never win.

  1. Rank 1

    Plan coverage + Zepbound Savings Card

    until Dec 31, 2026
    $25/mo

    ≈13 months of card benefit left at the maximum monthly benefit.

    • Commercial insurance that covers Zepbound (single-dose pen). US resident 18+. Government beneficiaries (Medicare, Medicaid, TRICARE) excluded.
    • As little as $25 for a 1-, 2-, or 3-month prescription. Max benefit $100 / $200 / $300 per 1- / 2- / 3-month fill. $1,300 calendar-year cap across up to 13 fills per calendar year. A month is 28 days and up to 4 single-dose pens, so 13 fills is a full year of 28-day cycles and the fill count binds at the same time as the dollar cap, not before it.

    Verified Sep 5, 2026 · zepbound.lilly.com

  2. Rank 2

    LillyDirect self-pay

    $449/mo

    Rises to $699/month if the refill condition is missed.

    • Refill within 45 days to keep this price
    • Lilly's direct channel. Vial and KwikPen at identical self-pay prices at every tier. Telehealth not included.

    Verified Sep 5, 2026 · lilly.com

  3. Rank 3

    Discount card at retail (GoodRx and similar)

    verify locally
    $299/mo
    • Dose- and pharmacy-dependent. Verify at your ZIP before relying on it.

    Verified Aug 29, 2026 · goodrx.com

  4. TrumpRx

    reference verify locally
    $299/mo
    • Starting-at price; routes you to LillyDirect pricing tiers by dose
    • Government referral site — does not sell drugs or process payments; issues coupons or routes to manufacturer DTC channels.

    Verified Sep 2, 2026 · trumprx.gov

  5. Retail list price (reference)

    reference verify locally
    $1,087/mo
    • Cited to TrumpRx, which displays $1,087 as Zepbound's list price; drugs.com stopped publishing it and now shows the LillyDirect self-pay tiers instead
    • Context anchor only — what the drug costs with no route at all. Walk-in cash at retail typically exceeds WAC.

    Verified Sep 2, 2026 · trumprx.gov

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Markdown Summary

Not your situation?

The same dose, priced the other ways it can be paid for. Most people arrive unsure which of these they are in — and it changes the answer more than anything else on this page.

Paying cash — uninsured, or not using insuranceCommercial plan — denied or excludedMedicareMedicaid

Fighting a denial instead?

Coverage criteria and appeal routes, from the payers' own documents:

Aetna (CVS Health)Blue Cross Blue Shield Federal Employee Program (FEP)CVS CaremarkElevance Health / Anthem (CarelonRx)Express Scripts (Evernorth / Cigna)HumanaKaiser PermanenteMedicaid (state-by-state)Medicare (Part D + GLP-1 Bridge)Optum Rx (UnitedHealthcare)