in 22 days NovoCare Pharmacy self-pay — Wegovy® tablets (oral semaglutide) 4 mg moves to $199/month See the changelog
WalletNoise

Zepbound® (tirzepatide) — 2.5 mg

Your cheapest verified route right now

verified price

$299 /month

LillyDirect self-pay

Verified Aug 8, 2026 · lilly.com

Per year at 12 fills
$3,588
A plan exclusion is not the end. Under ACA rules you have 180 days to appeal, and secondary indications (sleep apnea for Zepbound, cardiovascular risk for Wegovy) run through different criteria. See your PBM's policy page.
Before your next appointment: at 5 mg your cheapest route (LillyDirect self-pay) goes to $399/month — $100/month more than your current dose. WalletNoise shows the cost of a dose change, never whether to make one — that's your prescriber's call. Verified Aug 8, 2026 ·lilly.com
Ramp cost calculator

What the climb costs

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Both doses are yours to state, not ours to suggest. WalletNoise prices the schedule you describe and never recommends a dose, a target, or a pace — that is your prescriber's call.

12-month total $3,887 13 fills
Average per fill $299 peak $299
Flat at 2.5 mg $3,887 what multiplying today's price gives you
Cost per fill, 2.5 mg to 2.5 mg
  • 2.5 mg 13×
$0 $150 $300 2.5 mg — $299 $299 Aug2.5 mg — $299 Sep2.5 mg — $299 Oct2.5 mg — $299 Nov2.5 mg — $299 2.5 mg — $299 Dec2.5 mg — $299 Jan2.5 mg — $299 Feb2.5 mg — $299 Mar2.5 mg — $299 Apr2.5 mg — $299 May2.5 mg — $299 Jun2.5 mg — $299 Jul
Every fill, dated and priced (13)
  1. 1 Aug 10, 2026 2.5 mg LillyDirect self-pay $299
  2. 2 Sep 7, 2026 2.5 mg LillyDirect self-pay $299
  3. 3 Oct 5, 2026 2.5 mg LillyDirect self-pay $299
  4. 4 Nov 2, 2026 2.5 mg LillyDirect self-pay $299
  5. 5 Nov 30, 2026 2.5 mg LillyDirect self-pay $299
  6. 6 Dec 28, 2026 2.5 mg LillyDirect self-pay $299
  7. 7 Jan 25, 2027 2.5 mg LillyDirect self-pay $299
  8. 8 Feb 22, 2027 2.5 mg LillyDirect self-pay $299
  9. 9 Mar 22, 2027 2.5 mg LillyDirect self-pay $299
  10. 10 Apr 19, 2027 2.5 mg LillyDirect self-pay $299
  11. 11 May 17, 2027 2.5 mg LillyDirect self-pay $299
  12. 12 Jun 14, 2027 2.5 mg LillyDirect self-pay $299
  13. 13 Jul 12, 2027 2.5 mg LillyDirect self-pay $299
This is arithmetic, not a plan. Fills are spaced 28 days apart — the label's own supply length — and priced on the date each one falls, so dated price changes are already included. Your prescriber decides whether you step at all, and many people stay at a lower dose.
The label's own words (once weekly)

Initiate at 2.5 mg once weekly for 4 weeks. After 4 weeks, increase to 5 mg once weekly. The dosage may be increased in 2.5 mg increments after at least 4 weeks on the current dosage. The 2.5 mg dosage is for initiation and is not approved as a maintenance dosage. Maximum 15 mg once weekly.

Verified Aug 8, 2026 ·pi.lilly.com

Every route we can price

Verified prices outrank cheaper estimates. Reference rows inform, never win.

  1. Rank 1

    LillyDirect self-pay

    $299/mo
    • Lilly's direct channel. Vial and KwikPen at identical self-pay prices at every tier. Telehealth not included.

    Verified Aug 8, 2026 · lilly.com

  2. Rank 2

    Discount card at retail (GoodRx and similar)

    verify locally
    $299/mo
    • As low as; dose- and pharmacy-dependent — verify at your ZIP
    • Dose- and pharmacy-dependent. Verify at your ZIP before relying on it.

    Verified Aug 8, 2026 · goodrx.com

  3. TrumpRx

    reference verify locally
    $299/mo
    • Starting-at price; routes you to LillyDirect pricing tiers by dose
    • Government referral site — does not sell drugs or process payments; issues coupons or routes to manufacturer DTC channels. Displayed prices are starting-at tiers mirroring LillyDirect / NovoCare offers.

    Verified Aug 8, 2026 · trumprx.gov

  4. Retail list price (reference)

    reference verify locally
    $1,087/mo
    • Reference only
    • Context anchor only — what the drug costs with no route at all. Walk-in cash at retail typically exceeds WAC.

    Verified Aug 8, 2026 · drugs.com

Not your situation?

The same dose, priced the other ways it can be paid for. Most people arrive unsure which of these they are in — and it changes the answer more than anything else on this page.

Paying cash — uninsured, or not using insuranceCommercial plan that covers itMedicareMedicaid

Fighting a denial instead?

Coverage criteria and appeal routes, from the payers' own documents:

Aetna (CVS Health)Blue Cross Blue Shield Federal Employee Program (FEP)CVS CaremarkElevance Health / Anthem (CarelonRx)Express Scripts (Evernorth / Cigna)HumanaKaiser PermanenteMedicaid (state-by-state)Medicare (Part D + GLP-1 Bridge)Optum Rx (UnitedHealthcare)