in 4 days Aetna (CVS Health) — Zepbound back as additional preferred on templates See the changelog
WalletNoise

Zepbound® (tirzepatide) — 7.5 mg

Your cheapest verified route right now

verified price

$449 /month

LillyDirect self-pay

Verified Sep 5, 2026 · lilly.com

Per year at 12 fills
$5,388
Medicaid coverage of GLP-1s for obesity is state-by-state (13 states as of Jan 2026). See the Medicaid policy page for the current picture and your appeal rights.
Ramp cost calculator

What the climb costs

Close

Both doses are yours to state, not ours to suggest. WalletNoise prices the schedule you describe and never recommends a dose, a target, or a pace — that is your prescriber's call.

12-month total $5,237 13 fills
Average per fill $402.84 peak $449
Flat at 7.5 mg $5,837 what multiplying today's price gives you
Climbing saves $600 lower doses cost less on the way up
Cost per fill, 2.5 mg to 7.5 mg
  • 2.5 mg 3×
  • 5 mg 3×
  • 7.5 mg 7×
$0 $250 $500 2.5 mg — $299 Sep2.5 mg — $299 Oct2.5 mg — $299 Nov5 mg — $399 Dec5 mg — $399 Jan5 mg — $399 Feb7.5 mg — $449 $449 Mar7.5 mg — $449 Apr7.5 mg — $449 May7.5 mg — $449 Jun7.5 mg — $449 Jul7.5 mg — $449 Aug7.5 mg — $449

Fills at each dose on the way up

Reset to the label minimum
  • 2.5 mg −3 +
  • 5 mg −3 +
  • 7.5 mg then hold

Minus stops at the label's minimum interval — this never shows a schedule faster than the manufacturer's. Staying longer on a dose is yours to choose.

Every fill, dated and priced (13)
  1. 1 Sep 27, 2026 2.5 mg LillyDirect self-pay $299
  2. 2 Oct 25, 2026 2.5 mg LillyDirect self-pay $299
  3. 3 Nov 22, 2026 2.5 mg LillyDirect self-pay $299
  4. 4 Dec 20, 2026 5 mg LillyDirect self-pay $399
  5. 5 Jan 17, 2027 5 mg LillyDirect self-pay $399
  6. 6 Feb 14, 2027 5 mg LillyDirect self-pay $399
  7. 7 Mar 14, 2027 7.5 mg LillyDirect self-pay $449
  8. 8 Apr 11, 2027 7.5 mg LillyDirect self-pay $449
  9. 9 May 9, 2027 7.5 mg LillyDirect self-pay $449
  10. 10 Jun 6, 2027 7.5 mg LillyDirect self-pay $449
  11. 11 Jul 4, 2027 7.5 mg LillyDirect self-pay $449
  12. 12 Aug 1, 2027 7.5 mg LillyDirect self-pay $449
  13. 13 Aug 29, 2027 7.5 mg LillyDirect self-pay $449
This is arithmetic, not a plan. Fills are spaced 28 days apart — the label's own supply length — and priced on the date each one falls, so dated price changes are already included. Your prescriber decides whether you step at all, and many people stay at a lower dose.
The label's own words (once weekly)

Initiate at 2.5 mg once weekly for 4 weeks. After 4 weeks, increase to 5 mg once weekly. The dosage may be increased in 2.5 mg increments after at least 4 weeks on the current dosage. The 2.5 mg dosage is for initiation and is not approved as a maintenance dosage. Maximum 15 mg once weekly.

Verified Aug 31, 2026 ·pi.lilly.com

Every route we can price

Verified prices outrank cheaper estimates. Reference rows inform, never win.

  1. Rank 1

    LillyDirect self-pay

    $449/mo

    Rises to $499/month if the refill condition is missed.

    • Refill within 45 days of your last fill to keep this price (Zepbound Journey Program)
    • Lilly's direct channel. Vial and KwikPen at identical self-pay prices at every tier. Telehealth not included.

    Verified Sep 5, 2026 · lilly.com

  2. Rank 2

    Discount card at retail (GoodRx and similar)

    verify locally
    $299/mo
    • Dose- and pharmacy-dependent. Verify at your ZIP before relying on it.

    Verified Aug 29, 2026 · goodrx.com

  3. TrumpRx

    reference verify locally
    $299/mo
    • Starting-at price; routes you to LillyDirect pricing tiers by dose
    • Government referral site — does not sell drugs or process payments; issues coupons or routes to manufacturer DTC channels.

    Verified Sep 2, 2026 · trumprx.gov

  4. Retail list price (reference)

    reference verify locally
    $1,087/mo
    • Cited to TrumpRx, which displays $1,087 as Zepbound's list price; drugs.com stopped publishing it and now shows the LillyDirect self-pay tiers instead
    • Context anchor only — what the drug costs with no route at all. Walk-in cash at retail typically exceeds WAC.

    Verified Sep 2, 2026 · trumprx.gov

Share or post this breakdown

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Markdown Summary

Not your situation?

The same dose, priced the other ways it can be paid for. Most people arrive unsure which of these they are in — and it changes the answer more than anything else on this page.

Paying cash — uninsured, or not using insuranceCommercial plan that covers itCommercial plan — denied or excludedMedicare

Fighting a denial instead?

Coverage criteria and appeal routes, from the payers' own documents:

Aetna (CVS Health)Blue Cross Blue Shield Federal Employee Program (FEP)CVS CaremarkElevance Health / Anthem (CarelonRx)Express Scripts (Evernorth / Cigna)HumanaKaiser PermanenteMedicaid (state-by-state)Medicare (Part D + GLP-1 Bridge)Optum Rx (UnitedHealthcare)